Diabetic kidney disease (DKD) is a complication of diabetes that can damage the kidneys and lead to chronic kidney disease (CKD). It can also lead to kidney failure, also known as end-stage renal disease (ESRD).
High blood sugar : High blood sugar, or blood glucose, can damage the blood vessels in the kidneys.
High blood pressure : High blood pressure can damage the kidneys and make kidney damage worse.
Frequent urination at night (nocturia)
Tiredness
Headaches
Nausea and vomiting
Frequent daytime urination
Lack of appetite
Itchy skin
Leg swelling